We are seeking a Senior Scientist II with a background in molecular biology and/or microbiology to join our peptide display hit generation team. In this role, you will:
- Lead and manage technology development projects and therapeutic peptide hit generation efforts.
- Utilize phage-display and/or mRNA-display peptide technologies, including the design and generation of peptide display libraries, screening against therapeutic targets, and identification and maturation of pharmaceutically relevant hits.
- Drive internal hit generation initiatives and manage relationships with contract research organizations (CROs) to achieve project goals.
- Leverage our innovative peptide microarray platform to accelerate hit identification and maturation from peptide display campaigns.
This position offers the opportunity to play a key role in discovering impactful peptide therapeutics within a collaborative and innovative team.
Responsibilities:
- Lead the development of in-house peptide display workflows utilizing our proprietary peptide microarray platform to accelerate hit identification. Responsibilities include designing and generating display libraries, screening peptide libraries against therapeutic targets, performing next-generation sequencing, and conducting large-scale data analysis.
- Explore and assess advanced technologies for modifying peptide display libraries, such as chemical modification and incorporation of non-canonical amino acids.
- Use proprietary data analysis tools to efficiently analyze next-generation sequencing data and other large-scale datasets derived from peptide display libraries.
- Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise.
- Publish research in peer-reviewed journals and present work at scientific conferences.
- Seize opportunities to pursue project relevant leads that are in line with the group’s strategy.
- Demonstrates high proficiency across a wide range of relevant technologies.
- Proactively seek out new information in the literature and incorporate this into individual project(s) as well as the overall program.
- Primary author of publications, presentations, regulatory documents and/or primary inventor of patents.
- Understand and adhere to corporate standards regarding code of conduct, safety, and appropriate handling of materials
- May mentor/supervise a team of one or more and guide and evaluate the performance of those individuals.