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Sr. Scientist II, Molecular Biology/Microbiology

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Madison, Madison
Posted 7 days ago
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Job Description

We are seeking a Senior Scientist II with a background in molecular biology and/or microbiology to join our peptide display hit generation team. In this role, you will:

  • Lead and manage technology development projects and therapeutic peptide hit generation efforts.
  • Utilize phage-display and/or mRNA-display peptide technologies, including the design and generation of peptide display libraries, screening against therapeutic targets, and identification and maturation of pharmaceutically relevant hits.
  • Drive internal hit generation initiatives and manage relationships with contract research organizations (CROs) to achieve project goals.
  • Leverage our innovative peptide microarray platform to accelerate hit identification and maturation from peptide display campaigns.

This position offers the opportunity to play a key role in discovering impactful peptide therapeutics within a collaborative and innovative team.

Responsibilities:

  • Lead the development of in-house peptide display workflows utilizing our proprietary peptide microarray platform to accelerate hit identification. Responsibilities include designing and generating display libraries, screening peptide libraries against therapeutic targets, performing next-generation sequencing, and conducting large-scale data analysis.
  • Explore and assess advanced technologies for modifying peptide display libraries, such as chemical modification and incorporation of non-canonical amino acids.
  • Use proprietary data analysis tools to efficiently analyze next-generation sequencing data and other large-scale datasets derived from peptide display libraries.
  • Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise.
  • Publish research in peer-reviewed journals and present work at scientific conferences.
  • Seize opportunities to pursue project relevant leads that are in line with the group’s strategy.
  • Demonstrates high proficiency across a wide range of relevant technologies.
  • Proactively seek out new information in the literature and incorporate this into individual project(s) as well as the overall program.
  • Primary author of publications, presentations, regulatory documents and/or primary inventor of patents.
  • Understand and adhere to corporate standards regarding code of conduct, safety, and appropriate handling of materials
  • May mentor/supervise a team of one or more and guide and evaluate the performance of those individuals.
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