Position

We are looking for a Scientist experienced in protein chemistry and bioconjugation. You will be responsible for consistently executing core bioconjugation protocols, proactively contributing to the optimization of our workflows, and bringing your excitement for rigorous science and troubleshooting to our growing team. You will be joining a team with experience in protein chemistry and biochemistry and will work closely with a highly interdisciplinary team of creative experimental, computational, and hybrid scientists to advance our oligomedicines pipeline. 

Responsibilities

• Consistently execute core bioconjugation protocols for various antibody and oligo pairs.
• Purify and characterize bioconjugated products to ensure high-quality and reproducibility.
• Proactively identify and contribute to the optimization of existing bioconjugation and analytical workflows.
• Efficiently troubleshoot bioconjugation reactions and related biochemical assays.
• Accurately maintain detailed experimental records and contribute to scientific discussions.
• Effectively collaborate and communicate with the research team.

Required Qualifications

• PhD or equivalent experience in protein biochemistry, molecular biology, biological engineering, or a related field
• Experience with bioconjugation chemistry principles and methodologies (e.g., cysteine-based, lysine-based conjugation strategies, and/or enzymatic bioconjugation)
• Proficiency in basic protein purification techniques (e.g., affinity capture, protein quantification, gel electrophoresis, FPLC-based chromatography)
• Demonstrated practical experience with antibody production, purification, and handling
• Proven ability to troubleshoot biochemical assays and optimize experimental protocols
• A team-oriented mindset with a strong sense of ownership and follow-through

Preferred Qualifications

• 3+ years of hands-on wet-lab experience in protein production, purification, and biochemistry in an industry setting
• Experience with high-throughput screening or automation
• Familiarity with various analytical techniques for characterization of biomolecules (e.g., Mass Spectrometry, DLS, BLI, SPR)
• Familiarity with oligonucleotide chemistry or handling
• Experience establishing and troubleshooting enzymatic assays

This Role Might Be Perfect For You If

• You are excited by the challenge of independently proposing and implementing novel bioconjugation strategies to improve efficiency or yield
• You enjoy developing and validating new analytical methods to solve technical challenges
• You are motivated by the opportunity to identify and resolve complex technical challenges that unblock critical project bottlenecks