We are seeking a highly motivated in vitro electrophysiologist to join our collaborative Migraine and Pain drug discovery team.  The ideal candidate will bring deep expertise in ion channel biology and patch-clamp electrophysiology to support functional, pharmacological, and mechanistic studies that advance novel therapeutics.

Key Responsibilities Include:

• Design and execute manual patch-clamp electrophysiology experiments to characterize ion channel pharmacology, biophysical properties, and cellular excitability in relevant cell and disease models including primary, hiPSC-derived, and recombinant cell lines.
• Lead design, execution, and analysis of studies on automated patch-clamp platforms (e.g. SyncroPatch).  This will include both operation and training/guidance of more junior scientists on the instrument.
• Contribute to studies utilizing multi-electrode (MEA) recordings and complimentary fluorescence-based assays (e.g. calcium imaging, membrane potential assays) as needed.
• Support target identification, validation, and compound profiling to advance our Neuroscience pipeline, with a focus on pain-relevant ion channel families including both voltage-and ligand-gated channels.
• Apply broad cell and molecular biology skills to support mechanistic studies and complement electrophysiology-based work (e.g., cell culture, Western blot, Microscopy, transient transfection, RNAi approaches, etc).
• Read and adapt scientific literature to stay current in the field and advance techniques and innovative approaches
• Independently generate precise, reliable, and reproducible data in a timely manner; interpret and effectively communicate results to cross-functional project teams and diverse audiences.
• Contribute to scientific publications and present findings at internal and external scientific meetings and conferences.