We are seeking a highly motivated Senior Scientist I to join the Purification Process Development group within the Operations Product Development Science & Technology -Biologics organization.  Our group is responsible for purification process development across early- and late-stage of therapeutic proteins at AbbVie Bioresearch Center in Worcester, MA.  As one of leaders in the Purification Development group, this is a dynamic role which will drive the development and transfer of robust and effective purification processes for IND and BLA-enabling programs.  In addition, the ideal candidate will develop and apply next generation technologies (i.e. laboratory automation / robotics, modeling, advanced data analysis) and outside-of-the-box thinking to drive efficiency of the purification lab, platforms, and strategies.  The candidate will also coordinate and lead purification development activities within cross-functional CMC teams with a collaborative and progressive mindset.  

This position is an onsite role in a lab-based function. To be successful candidates must enjoy and thrive in an onsite, highly collaborative lab environment with daily face-to-face cross-functional interactions between scientists.

Responsibilities

• Development, optimization, scale-up, and tech transfer of purification processes for biologics candidates to support early and late-stage development  
• Maintain a high level of productivity and accuracy in the lab 
• Demonstrate creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals. 
• Proactively seek out new tools, techniques, and strategies to implement into the overall downstream platform, specifically with respect to the use of lab automation, robotics, and the use of next gen data analytics tools (ML/AI).  
• Represent purification development team and actively influence development strategy on cross-functional CMC teams  
• Work efficiently, collaboratively, and cross-functionally toward project timelines and goals   
• Transfer processes to pilot and GMP manufacturing

• Work with contract labs and carry out viral clearance studies  

• Write technical publications, reports, presentations, and regulatory filings including publishing research in peer-reviewed journals and presenting work at scientific conferences  
• Mentor and train junior scientists