Kyverna is seeking a highly motivated Sr. Director, Medical Science Liaison (MSL), who will engage scientifically with health care providers and medical and scientific experts to support the Medical Affairs Team’s strategic priorities and plans across Western United States. The Sr. Director MSL must have deep clinical/medical expertise to serve as a trusted resource to our external experts and internal teams and will embody Kyverna’s core values: Stay True to Why, Collaborate to Accelerate, Lead with Clarity, Boldly Innovative, and Own the Outcome.
LOCATION: Preferred locations Northern CA, NV, UT, TX, CO
TERRITORY: Western USA
REPORTS TO: Executive Director, Medical Affairs
TRAVEL: up to 50%
RESPONSIBILITIESProvide strategic leadership for Kyverna’s Field Medical function across Western USA, setting the vision, priorities, and operating framework for regional scientific engagement and external collaboration.Develop, lead, and maintain high-impact, long-term relationships with healthcare professionals, key opinion leaders, clinical investigators, academic research centers, professional societies, and patient advocacy groups to position Kyverna as a scientific and clinical thought partner.Serve as a senior scientific ambassador for Kyverna’s cell therapy platform and autoimmune disease portfolio, driving sophisticated, compliant scientific exchange to advance disease understanding, therapeutic adoption, and evidence-generation needs.Shape and influence Medical Affairs strategy by synthesizing high-quality field insights, including protocol feedback, treatment landscape evolution, unmet needs, real-world practice patterns, and competitive intelligence to inform clinical development, commercial planning, and lifecycle management.Provide senior oversight and partnership with clinical trial sites to anticipate and resolve barriers to identification, screening, enrollment, and retentionSupport commercial site activation, operational readiness, and optimal study execution as a member of site activation team.Oversee regional scientific activities such as advisory boards, congress planning, symposium support, investigator meetings, and scientific engagement initiatives; represent Kyverna at major international conferences as a senior leader.Support evaluation and development of investigator-initiated trials, scientific collaborations, and research partnerships, ensuring alignment with Kyverna’s medical strategy and organizational priorities.Build and mentor a high-performing regional MSL organization, including talent acquisition, training, coaching, and performance management to achieve excellence in scientific engagement and field execution.Ensure strategic alignment and cross-functional collaboration with Clinical Development, Safety, Regulatory, Commercial, Market Access, and Corporate Affairs, acting as a key advisor and scientific resource for internal leaders.Maintain deep and current expertise in autoimmune disease, cellular therapy, neuromuscular disorders, and emerging scientific literature to guide internal strategy and external engagement.Champion compliance, ethical scientific exchange, and adherence to all applicable laws, regulations, and company policies; ensure regional consistency in messaging, medical governance, and documentation practices.Ability to travel extensively across the region (up to 50 percent), including occasional weekends and short-notice requests, to fulfill leadership responsibilities.QUALIFICATIONS12+ years of progressive Medical Affairs experience with at least 5 years in a senior management or field leadership role, within neuromuscular therapeutics.Advanced scientific or medical degree (PhD, PharmD, MD, or equivalent) required.Demonstrated success developing and executing regional or global Medical Affairs strategies, including scientific engagement, evidence generation, and cross-functional alignment.Strong expertise in Myasthenia Gravis or related neuromuscular disorders strongly preferred. Expertise in neuroimmunology disorders also highly desirable.Proven ability to build, lead, mentor, and inspire high-performing MSL or field-medical teams.Exceptional verbal, written, and interpersonal communication skills with the ability to convey complex science and influence senior stakeholders.Highly strategic thinker with strong operational discipline; demonstrates independent judgment, adaptability, and the ability to manage multiple priorities in a dynamic environment.Strong collaborative mindset with a track record of successfully partnering across Clinical Development, Regulatory, Commercial, and Executive Leadership teams.The national salary range for this position is from $270,000 to $305,000 USD annually. This salary range is an estimate of what we reasonably expect to pay for this posted position, and the actual salary may vary based on various factors, including without limitation individual education, experience, tenure, skills and abilities, as well as internal equity and alignment with market data. This position is also eligible for bonus, benefits, and participation in Company’s stock option plan.
