We are seeking a Scientist, Macrocycle Design to apply state-of-the-art de novo design methodologies to computationally discover, develop, and evaluate therapeutic macrocycles. As a member of the design team in Seattle WA, you will leverage your knowledge of cutting edge methods in molecular design to augment Vilya’s existing design platform.

Vilya is a team-first organization, and we believe onsite work is essential to how we collaborate, move quickly, and build a strong culture. This is an onsite position in our Seattle office. Join us and help make a difference for patients!

RESPONSIBILITIES: 

• Collaborate with multi-disciplinary teams in the discovery and development of macrocyclic molecules with potency, selectivity, and in vivo stability using structure-guided approaches.
• Apply de novo design methods and integrated computational pipelines that generate macrocycle designs in support of discovery and hit optimization programs.
• Analyze data from experimental and computational assays to improve methodology throughout Vilya’s therapeutic discovery platform.
• Innovate Vilya’s computational design platform by building state-of-art de novo design workflows

PREFERRED QUALIFICATIONS:

• Ph.D. in a scientific or engineering discipline at the intersection of computational molecular design, medicinal chemistry, and drug discovery
• Hands-on experience with state-of-the-art protein design tools applied to de novo design of therapeutic molecules in conjunction with a deep understanding of molecular structure analysis methods
• Extensive hands-on experience with parallel job execution and high performance computing systems
• Expertise in working with high-level programing languages such as Python
• Expertise in integrating computational models into scalable and reproducible workflows
• Adept at working in a multi-disciplinary team

VILYA BENEFITS:

• Opportunity to work in a disruptive startup with a talented, experienced, and dedicated team
• 401(k) plan with employer matching for contributions
• Stock options
• Excellent medical, dental, and vision coverage
• Open, flexible vacation policy
• Support to attend professional conferences meaningful to your career growth
• Monthly cell phone and internet stipend
• Monthly wellness and commuter stipend

Salary Range : $120,000-$160,000/year