The Position

Senior Manager, Nonclinical Development

Evommune is seeking a Senior Manager, Nonclinical, to plan, execute, and oversee nonclinical studies in support of our immunology pipeline. This role will play a critical hands-on role in managing nonclinical studies at CROs and ensuring high-quality, compliant nonclinical deliverables aligned with development timelines.

Reporting to the Executive Director, Nonclinical Development, this position is well-suited for a scientifically strong, execution-oriented individual who thrives in a fast-paced biotech environment and enjoys translating strategy into action.

Responsibilities

Nonclinical Study Execution

• Support the design, execution, and oversight of nonclinical studies at CROs in collaboration with the Executive Director, Nonclinical Development
• Manage day-to-day interactions with external CROs, including study initiation, timelines, budgets, data review, and deliverables
• Monitor study progress to ensure alignment with program objectives, quality standards, and regulatory expectations

CRO & Vendor Management

• Serve as the primary operational point of contact for assigned CROs and external vendors
• Oversee and manage master service agreements, consulting agreements, study quotes, contracts, purchase orders, and invoices
• Review study protocols, amendments, reports, and raw data for accuracy, quality, and scientific integrity
• Manage study materials at GLP archiving facilities
• Track study milestones, risks, and dependencies; proactively escalate issues and propose mitigation strategies
• Participate in CRO qualification and maintain qualified vendors in collaboaration with QA

Documentation Support

• Manage study folders, data, and documents using in-house systems
• Ensure nonclinical documentation is inspection-ready and compliant with GLP and regulatory standards
• Perform QC review of study data, study reports, and regulatory documents as assigned
• Author and/or revised SOPs as needed

Operational Excellence

• Maintain accurate records of nonclinical activities, budgets, and timelines
• Support continuous improvement of nonclinical processes, templates, and vendor practices
• Operate with a high level of accountability, attention to detail, and scientific rigor

Qualifications

Education & Experience

• Bachelor’s degree (or equivalent experience) in a scientific discipline
• At least 10 years of experience in nonclinical/toxicology testing within biotech, pharma, or CRO environments
• Hands-on experience supporting IND-enabling nonclinical programs

Technical & Professional Skills

• Working knowledge of nonclinical studies and regulatory submissions
• Hands-on experience with nonclinical/toxicology/DMPK data generation, compilation, and/or review
• Proven ability to manage nonclinical studies conducted at CROs
• Direct experience supporting small molecule programs, including DMPK, toxicology, and ADME studies conducted at CROs
• Strong track record managing CROs and external vendors
• Solid understanding of Good Laboratory Practice (GLP) regulations
• Strong organizational, project management, and communication skills
• Ability to operate effectively in a lean, fast-paced biotech environment

Personal Attributes

• Highly execution-oriented with strong attention to detail
• Collaborative, proactive, and comfortable navigating ambiguity
• Able to balance scientific rigor with development speed and practicality

Compensation

The salary range for this position is $150,000-180,000 and the position may be eligible for performance-based bonuses and/or equity-linked compensation.  Salary ranges are determined by role, level and location and additional factors, including job-related skills, experience, and relevant education or training. We offer Company-sponsored benefits, which include: comprehensive health, dental and vision plans, and pet insurance. In addition, we provide a 401(k) plan, ample time off programs, paid parental leave, life insurance, disability insurance and an employee referral bonus program.

Evommune is proud to be an equal opportunity employer and will consider all qualified applicants for employment.