AbbVie is expanding its presence in Obesity Therapeutics and is seeking a Principal Scientist to participate in external innovation and diligence efforts to advance the early obesity pipeline.  This individual will report to a scientific director of obesity and primarily focus on external innovation activities for obesity assets.

Responsibilities: 

• Support external collaborations and licensing opportunities to diversify the pipeline by serving as the Obesity Discovery lead in Search & Evaluation diligence teams.  Use personal scientific expertise to advise on scientific merit and drive external innovation.  
• Perform literature/intelligence searches to determine scientific and technical approaches for discovery of novel obesity targets emphasizing CNS regulation of energy balance  with potential utility in additional indications (neurological disorders, autoimmune disorders).
• Serve as the Obesity Discovery lead in cross functional teams to expand obesity targets into other key therapy areas at AbbVie including but not limited to neuroscience and immunology.
• Coordinate in vitro/in vivo PoC studies for preclinical assets, working with contract research organizations and academic labs to complete key preclinical experiments.
• Apply experience to analyze preclinical PK, in vitro, in vivo data sets for obesity related assets, and to ensure scientific integrity throughout the process.
• Prepare scientific reports and presentations related to pre-clinical obesity assets.
• Design MoA experiments, review protocols, and data sets for late-stage clinical assets.
• Responsible for completing these tasks with minimal supervision.