Discovery Biotherapeutics and Genetic Medicine (BGM) at AbbVie is seeking a highly motivated research scientist to join the Cell and Functional Biology group at the Cambridge Research Center (CRC). Located in Cambridge, MA, the CRC is a uniquely collaborative environment where BGM, Immunology, Neuroscience, and Genomic Research Center teams work side by side.

In this role, you will be responsible for the conceptualization and execution of cell- and protein-based functional characterization assays for lead antibody identification and optimization. You will also collaborate to generate stage-gate-appropriate in vitro, cellular, and in vivo data packages supporting Proof of Concept (PoC) for Neuroscience and other therapeutic area programs.

The ideal candidate brings strong experience with cell-based assays, cell culture, and antibody screening, as well as significant expertise in flow cytometry, fluorescence-based assays, and imaging. Familiarity with high-throughput screening and multi-specific antibodies is highly valued. The successful applicant will be able to analyze, document, and present data effectively, and will possess excellent communication skills and comfort working in cross-functional teams.

Job Responsibilities:

• Support the development and implementation of cell-based fluorescent assays to enable function-first antibody screening across multiple therapeutic areas and drug discovery stages.
• Design, optimize, and validate assay protocols, ensuring robustness and reproducibility across projects.
• Analyze and interpret complex datasets, providing insights and recommendations for next steps in research projects.
• Stay current with technological advancements in cell-based assays, fluorescence applications, and imaging techniques to support the expansion of function-first assay design.
• Demonstrate scientific excellence through dedicated contributions to multiple projects in a fast-paced, multidisciplinary environment.
• Generate high-quality experimental data and perform scientific analysis to support multiple pipeline programs.
• Maintain detailed and accurate documentation of experimental procedures, results, and conclusions in electronic laboratory notebooks, technical reports, and presentations.
• Effectively communicate scientific findings and recommendations within project teams and cross-functional meetings.
• Continuously identify opportunities to improve laboratory methods, workflows, and scientific understanding.
• Maintain compliance with safety, quality, and good research practices while sustaining high laboratory productivity.