AbbVie’s Immunology R&D organization is expanding its early discovery team at the Cambridge Research Center in Cambridge, MA. We are seeking a highly motivated Scientist I to join our Respiratory Discovery team and contribute to the identification and validation of novel therapeutics for inflammatory lung diseases. The Cambridge-based early discovery team integrates human disease transcriptomic and multi-omic data sets with mechanistic in vitro studies to elucidate disease-driving pathways and advance innovative therapeutic strategies. The successful candidate will play a key role in providing support and the development of preclinical in vitro and in vivo models for respiratory diseases.

The ideal candidate is scientifically curious, collaborative, enthusiastic, skilled, and dedicated. This position requires passion, attention to detail, prior hands-on experience, and teamwork within a fast-paced drug discovery environment.

Key Responsibilities

• Sterile cell culture (cell lines and primary cells)
• Prior hands-on experience with primary innate and adaptive immune cells
• Process and analyze ex-vivo human and animal tissues for disease-relevant endpoints 
• Perform analyses using the following techniques:
  • Flow cytometry
  • Quantitative PCR
  • Protein analyses – ELISA, MSD and multiplex assays
  • Western blotting
• Develop and implement assays that monitor cellular processes
• Analyze data using appropriate statistical methods and communicate findings through presentations and scientific discussions
• Maintain detailed experimental records and ensure compliance with electronic laboratory notebook
• Candidates with prior in vivo experience will receive extra consideration

Key AbbVie Competencies:

• Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance
• Learns fast, grasps the “essence” and can change course quickly where indicated
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others and nurtures innovation to make possibilities real