Scholar Rock is a late-stage global biopharmaceutical company focused on developing and commercializing apitegromab for children and adults with spinal muscular atrophy (SMA) and other rare, severe, and debilitating neuromuscular diseases. As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the Company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more at ScholarRock.com and follow @ScholarRock on X and on LinkedIn.

Summary of Position:

We are seeking a motivated scientist with bioanalytical assay development experience to join our R&D team. This person will play a hands-on role in establishing pharmacokinetic, immunogenicity, and biomarker assays to evaluate novel therapeutic antibodies. The role provides exposure across the drug discovery process, as the successful candidate will support characterization and development of potential drugs at the research, preclinical, and clinical stages, playing a critical role in each.

Position Responsibilities:

Contribute to developing, troubleshooting, and executing a broad range of quantitative assays, including pharmacokinetic, pharmacodynamic, biomarker, immunogenicity, ligand binding, and cell-based assays to measure mechanism of action and potency.

Maintain detailed records of experimental protocols and data in laboratory notebooks in accordance with company policy and review others.

Analyze, interpret, and report experimental results in a small and large group setting.

Expected to work independently, participate in process improvement initiatives, and may function as a bioanalytical team lead on project team.

Work and communicate effectively as a team across functional boundaries in a dynamic, fast paced and highly matrixed environment.

Candidate Requirements:

BA/BS or MS in cell or molecular biology, biochemistry or related field with 2+ years of experience in drug discovery research

Candidates must have experience designing, developing, and performing ELISAs and/or ligand-binding assays

Experience with the development of pharmacokinetic, pharmacodynamic, and immunogenicity assays for therapeutic antibody drug discovery programs is highly desirable

Experience working with bioanalytical CROs and regulated bioanalysis is a plus

Demonstrated ability to work independently in a fast-paced team-oriented environment

Be able to design, execute, and troubleshoot experiments and propose creative solutions

Strong written and oral communication skills

Ability to succeed in a flexible, ambitious, and matrixed research and development environment

Scholar Rock is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

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Scholar Rock is hiring a Senior Associate Scientist I, Bioanalytical Assay Development

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