Job Description

Join AbbVie’s Biologics Discovery Sciences group and make a tangible impact in advancing innovative biologic therapies. As a scientist specializing in Biologics Purification, you will play a pivotal role in driving drug discovery, collaborating within a dynamic team dedicated to supporting transformative science that improves patient lives worldwide. Your expertise will help deliver high-purity multi-specific antibody-based biologic candidates with suitable purity/characteristics to support the advancement of vital in vitro (i.e. drug-like property assays, binding, cell-based assays, etc.) and in vivo studies (i.e. efficacy, non-GLP NHP PK, DRF, etc.). 

Key Responsibilities

• Lead small-scale (<1L) purification of multi-specific antibody biologics to support critical research assays and studies
• Design and execute advanced chromatography techniques and robust bioprocess development strategies to address production impurities and liabilities to deliver high quality antibody biologics to therapeutic areas
• Execute rigorous analytical characterization of molecules, end products, by-products, and process intermediates
• Apply Design of Experiments (DOE) with high throughput automation to optimize chromatography conditions for enhanced separation and resolution of complex protein mixtures
• Drive innovation to support continuous improvement in downstream biologics processes and advance automation initiatives
• Collaborate with multidisciplinary teams, translating molecular insights into functional results
• Present findings clearly to diverse audiences and document results with rigor