Position Overview: AbbVie’s Immunology Discovery Research organization seeks an impactful scientific leader to manage pioneering research in Gastroenterology/IBD.  A successful candidate should have a deep understanding of mucosal immunology, and will lead a team of discovery scientists within the broader Gastroenterology team focused primarily on delivering novel therapeutics from target identification through preclinical development and first-in-human studies. 

A deep understanding of establishing and validating novel disease-relevant translational endpoints, both immune and non-immune, in drug development as well as a proven track record of delivering drug candidates to various stages within the discovery pipeline are essential.  Candidates should also be able to demonstrate their ability to work cross-functionally in matrixed teams including management of collaborative external partnerships to advance innovative, patient-centric discovery programs.  This role requires strong scientific, people leadership, and strategic thinking.

The individual will:

• Integrate emerging scientific trends, patient-derived data, and utilization of humanized complex in vitro models (CIVMs) to identify/validate novel therapeutic targets for the treatment of IBD.
• Demonstrate exceptional strategic thinking by developing and executing robust research and drug discovery strategies that align with organizational objectives and drive innovation in autoimmune disease research.
• Provide scientific guidance and set direction for assay development, risk management, and research productivity.
• Ensure high-quality experimental design, incorporating early risk assessments and contingency planning.
• Foster cross-functional engagement across internal and external groups, including Chemistry, Biotherapeutics, Genetic Medicine, Precision Medicine, Clinical Development, and outside collaborations.
• Demonstrates exceptional ability to lead within a highly matrixed environment, effectively managing a team engaged across multiple programs and projects
• Actively participate in shaping overall disease area and target identification strategies, impacting the research group’s long-term vision and priorities.
• Communicate research progress and scientific direction to executive stakeholders.
• Champion mentorship and inclusive team culture, upholding AbbVie’s corporate standards.

An ideal candidate will have a background in mucosal immunology including both immune and non-immune cells and a proven track record for leading discovery programs from early-stage conception to clinical candidate selection.

Key Responsibilities

• Lead, manage, and develop a high-performing research team, ensuring their professional growth across all career stages.
• Oversee the planning and execution of in vitro and in vivo pharmacology studies, including the development and application of humanized CIVMs and PKPD assessments.
• Direct drug discovery programs, driving progression from early-stage conception to clinical candidate selection through strategic leadership and collaboration.
• Devise and implement research strategies that address critical scientific objectives and adapt to new internal and external scientific trends.
• Collaborate across multidisciplinary teams and with external research partners to accelerate program advancement.
• Develop and execute risk mitigation strategies and maintain study quality via robust experimental design, data analysis, and early contingency planning.
• Promote knowledge sharing by authoring publications and presenting to cross-functional and executive leadership as well as external partners.
• Mentor and train direct reports, fostering an environment that supports diversity, inclusion, and ongoing career development.