At AbbVie, we are dedicated to solving some of the world’s most complex and serious diseases. Our mission is to develop and deliver advanced therapeutics that change lives. We are looking for talented, passionate, and driven individuals to join our Biotherapeutics and Genetic Medicine (BGM) team. As a Senior Scientist in our siRNA group, you will be part of an innovative team focused on advancing RNA-based therapies that have the potential to revolutionize patient care. 

AbbVie is looking for a Senior Scientist I/II to join our siRNA group within the Biotherapeutics and Genetic Medicine (BGM) department. This role will involve designing and executing innovative experimental approaches to address key scientific challenges related to oligonucleotide therapeutics and to enable siRNA delivery for extrahepatic pipeline development. The successful candidate will drive scientific innovation, identify new methods and techniques, and collaborate across functions to support the development of novel RNA-based therapies. 

Responsibilities: 

• Lead research efforts within a cross-functional team to advance siRNA therapeutics development for ex-hepatic pipelines   
• Design, evaluate, and develop novel ex-hepatic siRNA delivery platforms for targeted delivery to tissues of interest 
• Conceive and execute proof-of-concept experiments to validate scientific hypotheses and address technical challenges with high-quality results. 
• Develop in vitro, ex vivo, and in vivo assays to assess siRNA candidates and delivery technologies in support of program objectives. 
• Work independently and maintain a high level of productivity in the laboratory, ensuring efficiency and scientific rigor. 
• Analyze and interpret multidisciplinary data to generate actionable conclusions and guide future experimental directions. 
• Acquire deep knowledge of RNA biology and siRNA therapeutics to support programs across multiple stages of development.    
• Collaborate and effectively communicate results with key stakeholders and cross-functional teams throughout the organization. 
• Contribute as a primary author to scientific publications, presentations, and/or as a primary inventor of patent applications. 
• Mentor and support junior scientists within the team.